Our lab is a multi-disciplinary research effort associated with the University of Minnesota Anterior Skull Base Surgery Center of Excellence. Our goal is to critically evaluate the diseases and therapies for anterior skull base disorders so that we can find better ways to care for our patients with these complex issues.
New technologies have broadened the ways we evaluate tissue with endoscopes (cameras and lenses that allow us to look inside the body). Special light filters and fluorescent dyes allow us to look through tissues to visualize blood vessels beneath the surface and more precisely map the edges of tumors during surgery. It is likely, though, that there is much more information we can gather using these technologies. We have an open study to better understand the applications and implications of these novel augmented endoscopic techniques.
Use of a narrow-band imaging blue light filter to highlight blood vessels in a meningioma extending into the nasal cavity.
Cancers that affect the nose, sinuses, and skull base are a rare but devastating set of diseases. Through a research grant from the Lions Charitable Foundation, we are investigating what factors predict better outcomes for our patients, how we might better treat and monitor patients with these diseases, and better understand the more global effects that cancer treatments have on our patients (for example, hearing loss related to surgery, chemotherapy, and radiation for these cancers).
In addition to using novel techniques and technologies to treat issues of the skull base, we have an ongoing effort to better evaluate our outcomes after skull base surgery. The diseases that affect the skull base and the treatments, particularly surgery, are complex and depend on many different factors, including genetics, exposures, and overall patient health (frailty), amongst many others. The goal of our outcomes research is to assemble these variables into a comprehensive picture that allows us to deliver the best care possible to our patients.